ATP, the principal energy currency of the cell, fuels most biosynthetic reactions in the cytoplasm by its hydrolysis into ADP and inorganic phosphate. Because resynthesis of ATP occurs in the ...

英国药理学：小檗胺和瓦巴因靶向Na+K+- atp酶与索拉非尼协同抑制肝癌 多激酶抑制剂索拉非尼是治疗晚期肝细胞癌(HCC)的一线药物。然而，肝癌患者对 ...

Researchers aim to apply these findings to produce more complex ATP- and ADP-coupled biomolecules to investigate their role and significance in cell function. “Our ultimate goal is to elucidate their ...

Mutations in the gene that encodes a protein called adenine nucleotide translocator ... generate most of the ATP needed to fuel body's cells and play an important role in high-energy demanding ...

In general, ATP concentrations must be maintained above 1 mM, with a high ATP/ADP.Pi ratio, in order to sustain the energy needed for RNA and nucleotide biosynthesis.

When ATP or ADP were added, this further increased gripping and friction, indicating two mechanisms of motor-DNA interaction -- nucleotide-dependent and nucleotide-independent.