Aldosterone binds to the cytosolic mineralocorticoid receptor (MR) in the distal convoluted tubules of kidneys and causes sodium retention in concert with exchange of potassium and hydrogen ions.

This review describes a method of analyzing acid–base disorders that incorporates insights from the traditional, bicarbonate-centered model and the Stewart (or strong ion) model (). 1–6 Acid ...

A deficiency in circulating levels of aldosterone or disease affecting the collecting duct may lead to type 4 renal tubular acidosis, which results in a defect in the distal secretion of hydrogen ...

Prevention and management of hyperkalemia in patients treated with renin–angiotensin–aldosterone system inhibitors. Jordan Weinstein, Louis-Philippe Girard, Serge Lepage, ... inorganic cation ...

Potassium is normally almost completely reabsorbed in the renal proximal tubules and is secreted in the distal tubules and collecting ducts in exchange for sodium; hydrogen ions compete with potassium ...