Autophagy is an intracellular process that targets various cargos for degradation, including members of the cGAS-STING signaling cascade. cGAS-STING senses cytosolic double-stranded DNA and triggers ...

However, the underlying molecular mechanisms of p53 and autophagy shows reciprocal functional interaction that is a major importance for cancer treatment and manegement. Additionally, several ...

Several signal transduction pathways that are triggered by common cellular stress as well as more specific signalling pathways can elicit both autophagy and apoptosis. Figure 2: Regulation of ...

Researchers’ understanding of the pathogenesis of rheumatoid arthritis has grown considerably in recent years, laying the ...

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling ...

A recent breakthrough from an international collaborative research team has unveiled the mechanism by which cells activate their recycling processes and generate “garbage bags” to eliminate proteins.

Background: Microglia-mediated inflammatory response directly affects ischemic stroke outcome. Autophagy is crucial in inflammatory response after cerebral ischemia. NLRC5 can be a positive or ...

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling ...

肉桂，又叫桂皮，是世界上使用最广泛的香料之一，还因其广泛的健康益处而受到认可，包括抗炎、抗菌和抗氧化特性等，由于具有这些有益健康的特性，肉桂被认为具有治疗多种人类疾病的潜力。此外，肉桂油提取物肉桂醛（CA）可以降低血糖、胆固醇，抑制癌细胞增殖，还具有 ...

autophagy induction signaling (A), membrane nucleation/AP formation (B), autophagy adaptor proteins (C) and AL formation/substrate degradation (e.g., lysosomal hydrolases or structural components)(D).