Deregulation of the mechanisms regulating aldosterone biosynthesis results in primary aldosteronism (PA), the most common form of secondary hypertension with an estimated prevalence of about 10% in ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Although the data suggest that HDLs inhibit adrenal aldosterone secretion, that effect would be opposite to some phenomena observed in vitro. Adrenal cortical cells bear receptors for lipoproteins, ...

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

National Tobacco Cultivation, Physiology and Biochemistry Research Center, Flavors and Fragrance Engineering and Technology Research Center of Henan Province, College of Tobacco Science, Henan ...

School of Medicine and Pharmacy, Key Laboratory of Marine Drugs Ministry of Education, Sanya Oceanographic Institute, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean ...

Aldosterone is known to bind to these receptors ... The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved about 1.5 hours after oral administration.

Natural ways to boost metabolism can be fun and easy. Simple things like eating more protein, high-intensity interval training, lifting weights, avoiding skipping meals, drinking the right things, ...

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Insulin-like growth factor (IGF) 1 is a member of a family that is involved in growth, development, cell differentiation, and metabolism. IGF1, IGF2 and insulin act primarily through tyrosine ...

Addison’s disease is a rare autoimmune disorder where the adrenal glands don’t produce enough vital hormones, causing fatigue, weight loss, low blood pressure, and potential life-threatening crises if ...