随着全球老龄化进程加速，衰老相关疾病如阿尔茨海默病（AD）、代谢综合征和肠道功能障碍成为重大公共卫生挑战。尽管衰老不可逆转，但延缓其进程被视为应对策略的核心。卤化8-羟基喹啉衍生物氯碘羟喹（Clioquinol, CQ）曾因神经毒性退市，近年却在骨关节炎和神经退行性疾病中展现出多效性，但 ...

Recent animal studies have shown that clioquinol – an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders – can reverse the progression of Alzheimer's, Parkinson ...

CQ is an old drug that was commonly used to treat fungal/protozoal infections of the gastrointestinal tract. Patients in Japan taking it developed subacute myelo-optic neuropathy which resulted in ...

Currently, Clioquinol is banned for internal use in many countries because of its side effects. In Japan in the late 1950s and 60s, the drug was found to cause a neurologic condition called subacute ...

Dec. 15, 2003 — The metal chelator clioquinol may reduce progression of Alzheimer's disease (AD) ... You are encouraged to report adverse drug event information to the FDA.

Drug Name : Clioquinol Clioquinol is an antifungal agent, prescribed for skin infections such as athlete's foot, jock itch and ringworm. Clioquinol inhibits fungal growth.

Eighteen of the patients were assigned to placebo and 18 received Prana's Alzheimer's disease drug, PBT-1 (Clioquinol) (the first of Prana's metal protein attenuating compounds (MPACs) to be ...

Drug Name : Clioquinol Clioquinol generic is an antifungal agent, prescribed for skin infections such as athlete's foot, jock itch and ringworm. This medication inhibits fungal growth.

03 Jan 2004. Results are in from the first pilot study to test the potential benefit of clioquinol in Alzheimer's disease (AD) patients, suggesting that the drug improves cognition and lowers plasma ...

11 Apr 2005. Sometimes it is not the drug that scuppers a clinical trial. Prana Biotechnology announced today that it is halting the much anticipated phase II/III clinical trial of its Alzheimer drug ...