The macroscopic dissociation constant for the enzyme–Tris complex that results in the formation of the C4a-S-cysteinyl-flavin (Kdapp) determined in this study is ∼14 mM at pH 8.0 (Table 1). The ...

This process has been demonstrated in vivo for LTB 4, but not for cysteinyl LTs (cysLTs). We examined transcellular cysLT synthesis during zymosan-induced peritonitis, using bone marrow transplants ...

Pulmonary eosinophilia developed while he was receiving treatment with montelukast, a chemically distinct cysteinyl leukotriene type 1 receptor antagonist. After discontinuation of montelukast therapy ...

Inhibition of the soluble epoxide hydrolase (sEH) enzyme diminishes degradation of epoxyeicosatrienoic acids, which can enhance their beneficial cardiovascular actions. Here, Imig and Hammock ...

Organophosphate esters (OPEs) are produced and released into the environment as plastic additives along with the production, use, and disposal of plastic. (18) Meanwhile, OPEs are widely distributed ...