This also leads to a decrease in the levels of prostaglandin (PG) E2, the anti-inflammatory PG, along with an increase in the synthesis of cysteinyl leukotrienes (LTs). Evidence suggests that ...

Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, ...

Deregulated apoptosis may also be the leading cause of cancer therapy chemoresistance. Caspase family of cysteinyl-proteases plays the key role in the initiation and execution of programmed cell death ...

Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC-MS) of acetaminophen and metabolites in mouse plasma Mouse plasma samples were analysed for acetaminophen (APAP) and five ...

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways have been found to ...

为解决病毒疫情治疗难题，Ondokuz May?s University 的研究人员开展蒙鲁司特钠（MLS）对牛呼吸道合胞病毒（BRSV）作用研究。结果显示 MLS 有 99% 抗病毒效果，极具研究价值。推荐科研读者阅读，探索药物新用与病毒防治新路径。

Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Basel 4002, Switzerland ...

Asthma is one of the major growth areas in therapeutics and many new drugs are currently in development. These drugs include improvements of existing classes of drugs, notably once-daily inhaled ...

1 Department of Pharmacology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy 2 Department of Thoracic Medicine, Imperial College School of Medicine at the National Heart and ...

Faculty of Chemistry, University of Wroclaw, 50-383 Wroclaw, Poland ...

Nine were silenced on maternal but active on paternal X mice, while two had the opposite pattern. The three maternal X genes silenced by the most cells were SASH3, toll-like receptor 7, and cysteinyl ...