Neutrophilic inflammation and a high level of free α-defensins are main features of chronic airway inflammation in alpha-1 antitrypsin-deficient (AATD) individuals. Despite the antimicrobial ...

Department of Immunology, Gastroenterology and Colorectal Surgery, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA Department of Medicine and The Will Rogers ...

New research in eGastroenterology identifies the unfolded protein response (UPR) as a crucial mechanism in maintaining ...

The extra-epithelial defence barrier includes antimicrobial proteins and peptides, such as lysozyme and defensins, which disrupt microbial cell walls, mucus coating that traps bacteria to be removed ...

imperial.ac.uk Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that have a number of important physiological roles including remodelling of the extracellular matrix, facilitating ...

Acute respiratory infections (ARIs) are a common cause of illness in children younger than 16 years and adults older than 65 ...

Neutrophils are innate immune cells that have a vital role in host defense systems. Neutrophil extracellular traps (NETs) are one of neutrophils’ defense mechanisms against pathogens. NETs comprise an ...

Dr. Natalie M. Curcio can't say enough good things about this breakthrough formula. "Defensins are natural peptides that stimulate master stem cells in the skin to make new basal cells," she explains.

Salmonellae are globally important Gram-negative bacterial pathogens that infect a range of hosts and cause several diseases, including gastroenteritis and typhoid fever. Orally ingested bacteria ...