A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds ...

These presenting cells might use a combination of lectin receptors, complement receptors and/or Fc receptors, and might potentially internalize antigen into neutral non-degradative endosomes prior ...

However, once a commitment to these degradative machines has been made, associated DUB activities can recycle ubiquitin, thereby contributing to ubiquitin homeostasis. Third, DUBs can be used to ...

Conversely, elevated testosterone levels, characteristic of the hormone environment inside male knees, led to reduced production of pro-inflammatory proteins and degradative enzymes, while ...

ATG7, one of the core proteins of autophagy, plays an important role in various biological processes, including the regulation of autophagy. While clear that autophagy drives angiogenesis, the role of ...

The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300071, P. R. China ...

Living organisms persist by virtue of complex interactions among many components organized into dynamic, environment-responsive networks that span multiple scales and dimensions. Biological networks ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The endosomal pathway is essential for ...

College of Bioscience and Bioengineering, South China University of Technology, Guangzhou, China. Jingtian Environmental Protection Technology Co. Ltd., Guangzhou, China;. The Key Lab of Pollution ...