更令人担忧的是，农民反映连续使用草甘膦（epsps抑制剂）、噻吩磺隆（als抑制剂）和2,4-d（合成生长素）后仍出现防治失败，但缺乏科学证据。这一现象背后，是否隐藏着新型多重抗性机制？

草甘膦抗性杂草常通过靶基因EPSPS扩增进化，但非EPSPS相关染色体结构异常未见报道。本研究发现抗草甘膦Amaranthus tuberculatus中存在约 6 μm 的大染色体（正常 2—3 μm），由着丝粒周围异染色质扩展和 5S rDNA 重复形成，无EPSPS且不传递给后代，为抗性染色体进化研究提供新方向。

结果发现，转基因烟草同时表达gr79 epsps和gat基因对草甘膦的抗性显著高于gr79 epsps或gat单基因烟草。 进一步利用农杆菌介导法将GR79 EPSPS-GAT双基因载体转化棉花，利用多种分子检测手段，获得含有一个和两个EPSPS-GAT表达盒插入的转基因棉花GGCO2和GGCO5，且GR79 EPSPS和GAT基因在转录和翻译水平均高表达。

We describe a mechanism for coincidence detection mediated by the interaction between backpropagating action potentials and EPSPs in neocortical pyramidal neurons. At distal dendritic locations ...

"Glyphosate targets an enzyme called EPSPS in the shikimate pathway. This enzyme is crucial to synthesizing three essential amino acids. Based on the structure of the EPSPS enzyme, we are able to ...

In a paper published on aBIOTECH, a new bio-breeding resource designated GG2 for glyphosate-resistant（GR）maize has been developed. The co-expression of GAT and GR79-EPSPS confers GG2 with high ...

Based on the structure of the EPSPS enzyme, we are able to classify 80-90% of microbial species into sensitive or resistant to glyphosate," says Docent Pere Puigbò, ...