In this study, we challenged rats with sucrose-sweetened water and investigated the potential effects of JNK inhibition by employing network analysis based on the transcriptome profiling obtained from ...

“At Mammoth, we have always believed in the therapeutic potential of CRISPR, and this study demonstrates that ultracompact systems can be potent and delivered in a single AAV vector to tissues outside ...

Delcath Systems, Inc. (Nasdaq: DCTH), an interventional oncology company focused on the treatment of primary and metastatic cancers of the liver, announced today it will host a conference call on ...

Neonatal HDL is synthesized both in the liver and intestine, which absorbs excess cholesterol from extrahepatic tissues and transports them to the liver, thus removing cholesterol from the body.

New research shows potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector This study describes the discovery ...

"At Mammoth, we have always believed in the therapeutic potential of CRISPR, and this study demonstrates that ultracompact systems can be potent and delivered in a single AAV vector to tissues outside ...

Extrahepatic vascular dilation, increased blood flow ... Utilizing nanocarriers enables precise drug delivery to specific cells or tissues, such as HSCs or LSECs. This not only enhances drug ...

The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...

that establishes proof-of-concept of NanoCas™, the first ultracompact CRISPR system capable of efficient extrahepatic editing when delivered systemically using a single adeno-associated viral (AAV) ...

The addition of nab-paclitaxel to gemcitabine and cisplatin did not improve survival in advanced biliary tract cancer.