为解决 TP53 移码突变胃癌治疗难题，江南大学附属医院研究人员开展相关研究，发现 GSK690 可抑制 TP53 Frameshift NLS 胃癌细胞生长。该成果为这类患者提供新治疗策略，极具科研价值，推荐大家阅读。

近日，团队在国际知名期刊PNAS上发表了题为“A frameshift mutation in JAZ10 resolves the growth versus defense dilemma in rice”的研究论文，在对茉莉酸信号途径JAZ10基因的编辑中，意外的发现了一种移码突变产生的新蛋白既提高水稻的生长又提高水稻的抗虫性，并解析了新蛋白的作用机制。

The frameshift mutation identified in B-CLL is likely to affect several important functional properties of Dok1 that are ascribed to its C-terminal region.

If you want to build a foundational understanding of genomics in both health and disease, it's important to be able to distinguish between the different type of genetic mutations that can occur. Here, ...

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The ...

Alan Duggan Borges, guitarist and producer for the experimental Irish noise-rockers Gilla Band, makes his own intense electronic music, recording as the Null Club. He’ll release a self-titled ...

C-terminal frameshift mutations generate viable knockout mutants with developmental defects for three essential protein kinases Peer-Reviewed Publication Beijing Zhongke Journal Publising Co. Ltd.

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not ...

Richard Warden - Richard Warden (Frameshift Counselling), Counsellor, Dundee, DD1, 01382 919379, I offer a select set of therapeutic approaches, along with elements of Cinema Therapy, online and ...

Vaccination of MSI-H colorectal cancer patients with frameshift peptide antigens: A phase I/IIa clinical trial.. If you have the appropriate software installed, you can download article citation data ...

Attitudes toward prevention options in Lynch syndrome (LS): Comparing frameshift peptide vaccination (FSPVAX), colonoscopy (COLO), and aspirin (ASA) chemoprevention.