The nuclear transfer and co-localization of VP4 and calnexin (a marker protein of ER), which were independent of their interaction, were unique to HepG2 cells. Expression of NSP1 could significantly ...

2016年5月， 中南大学湘雅二医院 在OncoTargets and Therapy（IF2.7001/4区）期刊上发表了一篇论文。在 发表9年后 ，因 图片组内重复 在pubpeer上被读者质疑。

Correspondence to Dr Maura Dandri, Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany; m.dandri{at}uke.de and Dr Marc Lütgehetmann, Institute of ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

We prepared ChIP DNA, as previously described 1, from HepG2 cells using a commercially available antibody (Santa Cruz Biotechnology) specific to the FOXA3 protein. After immunoprecipitating DNA (0 ...

Feb. 18, 2025 — Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

在构建 NAFLD 球体模型后，研究人员发现，球体在培养过程中逐渐形成了正常肝细胞的形态。FFA 刺激会抑制球体活力，而褐藻糖胶处理后，球体活力明显恢复。同样，FFA 会使球体中 TG 含量升高，褐藻糖胶则能让它降下来，油红 O 染色也再次证实了褐藻糖胶可以抑制球体中的脂质积累。这些结果充分表明，褐藻糖胶就像一位 “减脂小能手”，能够有效改善 FFA 诱导的脂质积累问题。

Ecological Importance Beyond its potential therapeutic applications, Macaranga conifera holds high ecological value as a food ...

研究人员发现 HepG2 细胞中 BAP1 主要在细胞核表达，于是他们通过实验敲低了 HepG2 细胞中的 BAP1 蛋白表达。神奇的事情发生了，原本 “安分守己” 的癌细胞变得异常活跃，细胞迁移能力显著增强，就像被解开了束缚的 “小怪兽”。而在主要表达细胞质 BAP1 的 PLC/PRF/5 和 Huh7 细胞中，敲低 BAP1 并没有对细胞迁移能力产生明显影响。