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IL-15:从实验室走向 FDA 批准,开启癌症治疗新时代的 “神奇因子”
在医学领域,癌症治疗一直是科学家们奋力攻克的难题。自上世纪 80 年代起,细胞因子(一类能调节细胞生长、分化、免疫功能等的小分子蛋白质)就被尝试用于癌症治疗。1986 年,干扰素(type 1)获批用于治疗毛细胞白血病,1992 年 IL-2 获批用于治疗肾细胞癌,随后它们还被用于治疗转移性黑色素瘤。IL-2 ...
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