Membrane proteins are proteins found in cell membranes, either at the surface or on intracellular organelles. Integral membrane proteins such as receptors and ion channels span the membrane.
The study of protein–protein interactions that involve integral membrane proteins has been thwarted by the difficulty of biochemical approaches and the unsuitability of genetic two-hybrid ...
With 20+ years of experience focused on membrane proteins, viruses, and antibodies, Integral Molecular's technologies have been integrated into the drug discovery pipelines of over 600 biotech and ...
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it ...
Engineered immune cells known as CAR-T cells are utilized in cancer treatment. Researchers at Uppsala University have recently identified that CAR molecules can be transferred from CAR-T cells to ...
Most of these processes are performed by proteins embedded within the cellular membrane. While some proteins only cross the membrane once, many do so several times, like a thread being woven into ...