Type-1 interferons regulate immune responses and the production of self-reactive antibodies that target red blood cells in a SCD mouse model.

The researchers engineered cancer cells to re-express Parkin and found that Parkin contributes to the production of interferons, which activate and attract T cells to fight the tumor. The findings ...

When they detect the presence of RNA viruses, they activate interferons through the mitochondrial antiviral signaling (MAVS) pathway. The MAVS protein resides on the outer membrane of a cell's ...