Parkin ubiquitinates mitochondrial outer membrane proteins, including MFN1 and MFN2. The mitophagy adapter proteins p62, NDP52, and optineurin connect LC3 to ubiquitinated proteins on the OMM and ...

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways have been found to ...

The best of Polygon in your inbox, every Friday.

Vicki takes your calls plus the best gossip from the county.

Click the FOLLOW button to be the first to know about this artist's upcoming lots, sold lots, exhibitions and articles ...

线粒体自噬与胃肠道肿瘤发生：线粒体自噬是线粒体生物发生的相反过程，可分为泛素（Ub）依赖性自噬和 LC3 介导的非 Ub 依赖性自噬。经典的线粒体自噬途径通常由 PINK1/Parkin 介导，PINK1 是一种丝氨酸 / 苏氨酸激酶，Parkin 是一种 E3 泛素连接酶。在 CRC 中 ...

Coastal gem steps from Palm Beach. This beautifully renovated home, just two streets from the coveted Palm Beach, offers a perfect blend of classic charm and contemporary upgrades. The home ...

Fixed cells were stained with a LAMP1 antibody in addition to either p62 (upper panel) or LC3 (lower panels) antibodies and imaged by confocal microscopy ... C. U2OS IMLS cells expressing PARKIN were ...

Paid parking tariffs across zone F areas in Dubai have been increased, as per a recent announcement by Parkin PJSC, the largest operator of paid public parking facilities in Dubai. The new fees ...

School of Pharmacy, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau SAR 999078, China Key Laboratory of Basic Pharmacology of Ministry of Education and Joint ...