Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

Liver cells are organized around the central veins to form hexagonal hepatic lobules that are powerhouses of liver metabolism and immune-metabolic regulators upon infection.

The portal tracts, which include branches of the hepatic artery ... Ongoing injury in the lobules, represented by inflammation, apoptotic hepatocytes, or acidophil bodies, and Kupffer cell ...

‘cooling down’the proinflammatory environment of the diseased liver, inhibiting further hepatic stellate cell activation and slowing down their collagen secretion, thereby reducing fibrosis (Fi ...

Azizoglu, PhD, University of North Carolina at Chapel Hill, who will investigate the Restructuring of the Hepatic Lobule Vasculature in Acute Chemical Liver Injury. Vijay Pandyarajan, MD ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...