Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...

Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...

Researchers say if their results are confirmed through further study they are optimistic the approach could be used to treat chronic infections for the first time.

Feb. 6, 2025 — The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver ...

Liver-Related Causes Any dysfunction of the liver can affect bile production. Liver cells (called hepatocytes) produce bile by secreting bilirubin, bile acids, cholesterol, proteins, and water into ...

PROX1 acts as a molecular ‘cell fate guardian’ in hepatocytes, preserving liver cell identity throughout life by actively repressing unwanted plasticity. PROX1 loss impairs liver regeneration ...