HCC develops in the background of cirrhosis or chronic liver disease, and usually has a capsule, seen as high signal peripheral rim enhancement on venous or equilibrium phase images. Fibrolamellar ...

Cells were washed with permeabilization buffer and stained for intracellular IL-17A. Non-parenchymal liver cells were incubated with monoclonal antibody 2·4G2 for FcR blocking (BioLegend, San Diego, ...

“These viruses can cause cell death, and chronic infections can lead to scarring, or fibrosis,” says Sudha Kodali, MD, a hepatologist in Sugar Land, Texas, and a volunteer for the American ...

Objective Sustained inflammation originating from macrophages is a driving force of fibrosis progression and resolution. Monoacylglycerol lipase (MAGL) is the rate-limiting enzyme in the degradation ...

imperial.ac.uk Objective Acute liver failure (ALF) is characterised by overwhelming hepatocyte death and liver inflammation with massive infiltration of myeloid cells in necrotic areas. The mechanisms ...

For this study, small pieces (3–5 cm3) of postmortem human liver (right central parenchyma), kidney (wedge piece containing cortex and medulla), and brain (frontal cortex) samples were ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

The samples analyzed through bulk RNA sequencing provided a comprehensive view of gene expression within liver tissues rather than single-cell sequencing, which may not represent cellular ...

Institut Pasteur, Université Paris Cité, Malaria Infection and Immunity, BioSPC, Paris, France Microbiology Department - A Coruña Hospital, MicroTM-INIBIC, A Coruña, Spain Affinity Reagents Team, ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...