Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

NK cells are a prominent class of non-parenchymal cells (NPCs) within the hepatic immune microenvironment, comprising approximately half of the total lymphocytes in the human liver.

Emerging evidence highlights the pivotal roles of non-parenchymal cells (NPCs)—liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs), Kupffer cells (KCs), and innate immune ...

Acute and chronic liver injury models were performed in wild type and Trem-2-/- mice. Primary liver cells from both genotypes of mice were isolated for in vitro experiments. Results TREM-2 was ...

Integrative multi-omic analysis of parenchymal cells reveal TF dynamics underlying altered cell states in cirrhotic liver To further interrogate the gene regulatory mechanisms underlying these altered ...

Understanding how cells form tissues is an essential component in systems biology that involves the generation of tissue models. Generating such a tissue model requires a proper reconstruction of the ...

Parenchymal and non-parenchymal liver cells as well as immune infiltrating cells contribute to mechanisms of liver injury and repair. In this context, cell-type–specific activation of Jnk family ...

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for ...

Non-parenchymal cells like hepatic stellate cells (HSCs), Kupffer cells (KCs), and liver sinusoidal endothelial cells (LSECs) play a key role in fibrosis development.