This inflammation can lead to changes in the liver if it persists. Changes like fibrosis, or scarring of the tissue in the liver, may lead to cirrhosis. “Liver inflammation is common and can be ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

Cancers can also occur in the bile ducts outside the liver. Liver Biopsy A needle is inserted into the abdomen and is used to take a small sample of liver tissue. The sample is then examined closely ...

Some nutrients must be changed (metabolized) in the liver before they can be used for energy or to build and repair body tissues. It makes most of the clotting factors that keep you from bleeding too ...

Twenty-one male C57BL/6J mice (weight 30 g, aged 8–10 weeks) were purchased from Sipeifu (Beijing, China) and randomly divided into three groups to obtain liver tissue for molecular and histological ...

So, TREM2 in liver macrophages is critical for promoting tissue repair and preventing excessive fibrosis, suggesting its potential as a therapeutic target. In addition, the study also demonstrates ...

At the end of the experiment of each different model, mice were sacrificed following blood collection. Subsequently, the mice were dissected and the liver tissues were harvested. Some portions of the ...

Feb. 6, 2025 — The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver ...

A portion of liver tissue (left lateral liver lobe) obtained from each group was placed in 4% paraformaldehyde for more than 24 h, dehydrated, and embedded in paraffin wax. Next, the liver tissues ...

This work presents an important mouse model for a liver-specific depletion of the Survival Motor Neuron (SMN) protein, where the liver retains 30% of functional full-length SMN protein. The authors ...

The control individuals that were included had no history of diabetes, alcohol abuse or viral hepatitis. Control samples were taken from normal liver tissues at the edge of resected hemangioma.

Liver diseases are any diseases that affect the functioning of the liver. Liver diseases can be inherited (such as Wilson disease and alpha 1-antitrypsin deficiency) or acquired (for example ...