Furthermore, HPK1-N causes differentiation of progenitor cells towards the monocytic lineage. In contrast to full-length kinase, HPK1-N is constitutively active causing sustained JNK activation ...

The finding that increased levels of C/EBPα favor granulocytic over monocytic differentiation in U937 cells suggests that, as with PU.1 and GATA-1, C/EBP levels may play a role in lineage ...

Acute monocytic leukemia is a subtype of acute myeloid leukemia (AML) and is denoted as AML-5 or M5. ... Diagnosis criteria: >80% of monocyte lineage cells should be monoblasts ...

Acute monocytic leukemia (AML-M5) is a subtype of AML, in which at least 80 percent of the affected blood cells are a type of white blood cell called monocytes. Half of the people diagnosed with ...

Background: Human monocytic ehrlichiosis (HME) is a tick-borne illness caused by Ehrlichia chaffeensis. Data about disease in children have been largely derived from case reports or small case ...