Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Diet plays a pivotal role in influencing autoimmune diseases like multiple sclerosis (MS), inflammatory bowel disease, and rheumatoid arthritis. Despite this, the underlying mechanisms linking diet to ...

Irritable bowel ... intestines and heightened sensitivity to abdominal pain, even though their organs showed no physical damage. The cVSDS animal model involved having the subject mouse repeatedly ...

The complete small and large intestine of the mice was resected en ... and an optical micrometer. For each mouse, we determined the size of 3–15 adenomas located in the last 5 cm of the terminal ...

Nerve–Gut Research Laboratory, Hanson Institute, Royal Adelaide Hospital, Australia Objective: Intestinal infection ... In vitro preparations of mouse colorectum with attached pelvic or splanchnic ...

2014). In crypt development in the small intestine in the mouse, MYC signalling pathways are significantly enriched. Laser capture microdissection followed by functional genomics analysis of ...

These new probes promise to outperform calprotectin, the only clinically approved biomarker for inflammatory bowel disease ... to detecting disease in the small intestine, the long, thin tube ...

A promising experimental blood test has shown the ability to accurately detect colon cancer with 81% accuracy in patients and correctly rule it out in 90% of healthy individuals. This less ...

The incidence of intestinal obstruction in pregnancy varies from 1 in 1,500 to 1 in 66,500 pregnancies. [39] Although adhesions is the most common cause, volvulus (25%), intussusception (5% ...

Depending on the severity of the condition and how the body responds to other treatments, the surgery may involve removing part of the colon, or large intestine. A person may still poop when they ...