Cancer targeting receptors, TCR and CAR, are introduced to the activated T cells to empower them against special type of cancer. ζ subunit of CD3 on the surface of T cell is essential for triggering ...
Functionally bivalent non-covalent Fab dimers (Bi-Fabs) specific for the TCR/CD3 complex promote CD3 signaling on T cells. While comparing functional responses to stimulation with Bi-Fab, F(ab’)2 or ...
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