Interrupting signals exchanged between tumors and the nervous system could become a critical pillar of cancer care ...

More information: Alexander R. Goldberg et al, Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition, Neuron (2025). DOI: 10.1016/j.neuron.2024.12.026 Provided by ...

Using a combination of techniques and cutting-edge tools, such as in-vivo two-photon imaging, the team investigated neuronal changes in a glioma mouse model. This approach allowed for precise ...

Gliomas can return months or even years after surgery, and the prospect of recurrence is naturally concerning for patients. Fortunately, recurrent gliomas can often be detected early through continued ...

As a result, several methylation features (sites) were found to relate to glioma subclasses, which are annotated onto multiple genes, such as FLJ37543, LCE3D, FAM89A, ADCY5, ESR1, C2orf67, REST, EPHA7 ...

Published in Neuron, the research highlights how gliomas infiltrate the brain's cortex, disrupt neuronal function, and trigger hyperexcitability, while also demonstrating a rapid, promising ...

Gliomas are complex brain tumors that require a detailed assessment to determine their grade, location, and best course of treatment. MRIs are used throughout the treatment process. This type of ...