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STN-DBS “解密” 帕金森病:抑制 TrkB 簇聚集,守护多巴胺能神经元
以前,我们对 STN - DBS 潜在的神经保护作用只是猜测,现在研究人员通过实验证实了它在减少 TrkB 簇形成和保护多巴胺能神经元方面的作用。这不仅让我们对大脑中复杂的神经调节机制有了更深入的了解,也为未来开发更有效的帕金森病治疗方法提供了重要线索。比如,我们可以根据这些发现,进一步优化 STN - DBS 的治疗方案,找到最佳的刺激参数,提高治疗效果。而且,TrkB ...
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