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Studies on NMR methodology of characterizing the structure of polymers and biopolymers based on understanding of NMR chemical shift/structure correlation by solution-state and solid-state NMR ...
The NMR-based analysis enabled the mapping of each step in the conversion process —from complex mixtures to multiple high-value chemical products.
NMR spectroscopy is a critical tool for linking protein structure, dynamics and interactions to protein function, but is challenging to apply to high-molecular-weight proteins.
Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) are indispensable analytical tools to provide chemical fingerprints in metabolomics studies. The present study evaluated ...
Together with a dynamic-B-field transceiver with a planar coil for micro-NMR assay and thermal control, the system demonstrates: 1) selective biological target pinpointing; 2) protein state analysis; ...
Neutral open-shell molecules, in which spin density is delocalized through a helical conjugated backbone, hold promise as models for investigating phenomena arising from the interplay of magnetism and ...
The Royal Society of Chemistry NMR Discussion Group (NMRDG) is pleased to announce its annual postgraduate meeting, to be held at University College London on 16-17 June 2025. This gathering brings ...
Tris Pharma to Debut Positive Results of Intranasal (Snorting) Human Abuse Potential Study of Cebranopadol, an Investigational First-In-Class Oral Dual-NMR Agonist for the Treatment of ...
编辑推荐: 本研究从土壤来源的杂色曲霉QC812中分离出两种新型化合物——18,22-环甾醇aspersteroline A(1)和DMOA衍生meroterpenoid asperterpene O(2),以及三种已知化合物(3-5)。通过NMR、HRESIMS等技术解析结构,并证实化合物1和3对HL-60肿瘤细胞株具有中等细胞毒性(IC50 分别为8.6和14.9 μM),为抗肿瘤药物 ...
Here, using NMR, we explore slow (subsecond) and fast (submillisecond to millisecond) structural transitions sampled by the isolated C-terminal domain of RfaH. In addition to the predominant, ...
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