In a double-blind trial, we randomly assigned 14,264 patients with nonvalvular atrial fibrillation who were at increased risk for stroke to receive either rivaroxaban (at a daily dose of 20 mg) or ...

Traditional risk factors and prior CV disease aren’t the whole story when it comes to increased rates of all-cause mortality in patients with NVAF, say these researchers. Here’s what ...

Expert Rev Cardiovasc Ther. 2012;10(4):433-439. Another important trial that needs discussion is the ROCKET AF trial. ROCKET AF studied 14,264 patients with nonvalvular AF and compared the Factor ...

Atrial fibrillation is an irregular heart rhythm. There are several types, depending on how long the irregularity lasts and its cause. Learn more here.

Cite this: Anticoagulants for Nonvalvular Atrial Fibrillation (NVAF) -- Drug Review - Medscape - Feb 07, 2003. Abstract and Introduction Methodologic Problems in the Randomized Controlled Trials ...

Background: Nonvalvular atrial fibrillation (AF) is common in elderly patients, who face an elevated risk of stroke but difficulty sustaining warfarin treatment.

However, major bleeding rates were lower for apixaban, driven by differences in gastrointestinal bleeding and other nonspecified bleeding (45.57 vs 31.21 per 1,000 person-years; adjusted HR 1.42 ...

We randomly assigned 2124 participants with nonvalvular atrial fibrillation who had undergone PCI with stenting to receive, in a 1:1:1 ratio, low-dose rivaroxaban (15 mg once daily) plus a P2Y 12 ...

Tenecteplase Superior to Alteplase for Stroke Treatment Most people with nonvalvular atrial fibrillation (NVAF) should be taking oral anticoagulants to prevent stroke. Antonio Culebras, MD, and ...

In A Subanalysis, The Benefits Of Eliquis® (apixaban) Vs. Warfarin In Reducing The Risk Of Stroke In Patients With Nonvalvular Atrial Fibrillation Were Consistent, Regardless Of Blood Pressure ...

Michael B. Bottorff, PharmD: We’ve been using warfarin for atrial fibrillation and stroke prevention for quite some time, now. It’s an indirect acting anticoagulant. The way it works is that ...

31. Deitelzweig SB, Buysman E, Pinsky B, et al. Warfarin use and stroke risk among patients with nonvalvular atrial fibrillation in a large managed care population. Clin Ther. 2013;35(8):1201-1210 ...