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Here we present a microRNA (miRNA) knockdown application, based on the use of Locked Nucleic Acid (LNA™)-modified probes. The use of LNA for the knockdown of miRNA is particularly effective ...
In a joint initiative between the Universities of Geneva, Lausanne and Bern, and the EPFL the Dubochet Center for Imaging ...
The variety of potentially useful dyes or haptenes available for fluorescent nucleic acid hybridization assays is far greater than what can be obtained from commercial sources 1,2. Since this ...
Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...
The team discovered that IPMK binds directly to SRF, altering the three-dimensional structure of the SRF protein ... More information: Hyoungjoon Ahn et al, Single-molecule analysis reveals that IPMK ...
Advancements in manufacturing technologies is a key driver driving nucleic acid therapeutics CDMO market revenue growth.
No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.
The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are ...
The unbalanced coagulation of blood is a life-threatening event that requires accurate and timely treatment. We introduce a user-friendly biomolecular platform based on modular RNA-DNA anticoagulant ...
Correction for Smith et al., A twist grain boundary phase in aqueous solutions of the nucleic acid tetramer GTAC ...
Metal-dependent DNA and RNA nucleases are enzymes that cleave nucleic acids with great efficiency and precision. These enzyme-mediated hydrolytic reactions are fundamental for the replication, repair, ...