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双相情感障碍患者血清紧密连接蛋白ZO-1与occludin水平异常:血脑屏障 ...
本研究针对双相情感障碍(BD)复杂的病因学机制,聚焦血脑屏障(BBB)紧密连接(TJs)关键蛋白occludin和ZO-1的血清水平变化。通过对比40例BD患者(含20例躁狂发作和20例缓解期)与40名健康对照,发现患者组两种蛋白水平显著升高(ANCOVA校正混杂因素后P<0.05),提示BBB ...
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