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14 天
CLL发生Ritchter转化,表型上有什么特征?跟预后有什么关系?
慢性淋巴细胞白血病(CLL)患者中,约10%会经历一种致命转变——转化为侵袭性更强的弥漫大B细胞淋巴瘤(DLBCL),这一过程被称为“Richter转化”(RT-DLBCL)。尽管此类患者的中位生存期不足1年,但关于其生物学特征的研究长期匮乏。202 ...
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