Plasmacytoid dendritic cells are known for their ability to produce large amounts of type I interferons, which can contribute to autoimmunity. Research now shows that this pathogenicity involves a ...

Blastic plasmacytoid dendritic cell neoplasm (BPDCN): Prognostic factors and outcomes in 68 Mayo Clinic patients.

Outcomes in patients (pts) younger than 50 years old (yo) with treatment-naïve blastic plasmacytoid dendritic cell neoplasm (BPDCN) treated with tagraxofusp (TAG): Subanalysis of a phase 1/2 trial..

An expert discusses how addressing unmet needs in early diagnosis, treatment options, and long-term management, alongside exploring targeted therapies, combination approaches, and advancements in stem ...

AbstractBackground:. Plasmacytoid dendritic cells (pDCs), a unique type of innate immune cells, are known to play an important role in fighting viral infections, especially due to their capacity to ...

Blastic plasmacytoid dendritic cell neoplasm is a type of blood cancer. It originates in plasmacytoid dendritic cells, a part of the immune system. Learn more.

Single-cell RNA-seq data and transgenic models revealed B-plasmacytoid dendritic cells (B-pDCs) represent a phenotypically and functionally distinct common lymphoid progenitor-derived pDC lineage ...

Innate immune system cells control megakaryopoiesis They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis).

Plasmacytoid dendritic cells (pDCs) are innate immune cells that produce type I interferon (IFN-I) and other cytokines in response to virus-derived nucleic acids. Persistent viruses often cause ...