BMJ18 天
SGLT2 inhibitors alleviated podocyte damage in lupus nephritis by decreasing inflammation ...
The podocytes were cultured for 10 days at 37°C without ITS to induce differentiation. After the differentiated of podocytes had matured, the culture was supplemented with purified IgG from serum of ...
Medical Xpress19 天
Lab findings support concept that reducing neuroinflammation could help fight Alzheimer's
Get Instant Summarized Text (Gist) Reducing neuroinflammation by targeting the NLRP3 inflammasome in microglia shows promise for Alzheimer's treatment. Inhibiting NLRP3 not only decreases ...
Frontiers20 天
Focus on podocytes: diabetic kidney disease and renal fibrosis — a global bibliometric ...
Background: Diabetic kidney disease (DKD) is a common pathway to End-stage renal disease (ESRD). Podocytes are crucial due to their dual barrier functions in kidney diseases. Their role in renal ...
Medscape21 天
From the Periphery of the Glomerular Capillary Wall Toward the Center of Disease
Injury of podocytes, if recognized at all, has been considered a late consequence caused by increasing proteinuria rather than an event inciting diabetic nephropathy. However, recent biopsy ...
Frontiers2 年
SARS-CoV-2 Employ BSG/CD147 and ACE2 Receptors to Directly Infect Human Induced Pluripotent ...
We employed a human induced pluripotent stem (iPS) cell-derived model to investigate the affinity of SARS-CoV-2 for kidney glomerular podocytes, and examined the expression of host factors for binding ...