Dendritic cells (DCs) induce infection-protective immune memory, which has yet to be exploited for cancer therapy. Here we show that type 1 DC vaccines quantitatively and qualitatively favors anti ...

Plasmacytoid dendritic cells are known for their ability to produce large amounts of type I interferons, which can contribute to autoimmunity. Research now shows that this pathogenicity involves a ...

Learning Objectives: 1. Identify the key roles of dendritic cells in cancer immunotherapy, including their use as antigen-loaded vaccines and intratumoral adjuvants. 2. Explain the strategies used to ...

Disclosures Immunotherapy. 2012;4 (10):1053-1061. Abstract and Introduction Abstract Plasmacytoid dendritic cells (pDCs) are specialized APCs implicated in the pathogenesis of many human diseases.

Go on an adventure into unexpected corners of the health and science world each week with award-winning host Maiken Scott. The Pulse takes you behind the doors of operating rooms, into the lab ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

A visitor pays respects at the Pulse nightclub shooting site in Orlando, the day after the 9th anniversary of the 2016 massacre that killed 49, Friday, June 13, 2025. (Joe Burbank/Orlando Sentinel) ...

Glial cells help support, connect, and protect the neurons of the central and peripheral nervous systems. They come in many shapes, sizes, and types, each performing specialized functions.

As we approach the nine-year mark of the Pulse tragedy, Orlando continues to receive love from around the nation. Artist Jay Critchley from Massachusetts has again sent ribbons to honor the 49 ...

This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...

The former Pulse nightclub, site of the 2016 mass shooting that killed 49 patrons, south of downtown Orlando, Fla., Oct. 18, 2023.

She was among those who decided to go inside Pulse on Thursday, which was once a popular LGBTQ+ nightclub. And she says even though it was difficult, she doesn’t regret her decision.