The researchers validated their results by injecting the lab-grown spermatogonia stem cells into mouse testes. There, the cells underwent normal spermatogenesis, producing functional spermatids.

Tight junctions are a type of cell-cell junction found in epithelia that forms a barrier that is impermeable to the majority of soluble molecules between the two sides of the epithelium.

Focusing on adult-stage germ cell datasets, unbiased clustering analysis revealed a clear UMAP embedding representation that captured the dynamic progression of germ cells from undifferentiated SPG to ...

At the cellular level, fluorescence was detectable (B1-B3) in germ cells including Spermatogonia (Sg), Spermatocytes (Scytes) and round Spermatids (RStides), as well as (C1-C3) in Sertoli cells (SC). ...

When you need a break from the hustle and bustle of Canada's biggest city, you can hop on a quick, 15-minute ferry ride to the Toronto Islands. Amidst the towering skyscrapers of the city's ...

For the male genetic materials to reach and fertilize the egg, spermatozoa must contend with numerous environmental changes in a complex and highly sophisticated process from generation in the testis, ...

This valuable study presents data suggesting the critical roles of two ancient proteins, XAP5 and XAP5L, in regulating the transcriptional program of ciliogenesis during mouse spermatogenesis. The ...

School of Environment, Hangzhou Institute for Advanced Study, University of the Chinese Academy of Sciences, Hangzhou, Zhejiang 310024, China College of Life Science, China Jiliang University, ...

There are a significant number of words, phrases and acronyms that appear when talking about race and ethnicity which often change depending on the context of the conversation. Language is ...

Background Azoospermia is diagnosed when sperm cells are completely absent in the ejaculate even after centrifugation. It is identified in approximately 1% of all men and in 10%–20% of infertile males ...