Specialized urea transporters have evolved to achieve rapid and selective urea permeation in the mammalian kidney, a process ultimately necessary for water re-absorption. Here, the X-ray crystal ...

A study led by the Universitat Autònoma de Barcelona identifies different patterns of three-dimensional chromosome folding throughout mammalian evolution and provides new interpretative ...

Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and ...

The structure of mammalian fatty acid synthase reveals how different catalytic domains are excised or inserted in various members of this family to yield multi-enzymes capable of synthesizing a ...

Structure of ATPase, the world's smallest turbine, solved First complete structure of mammalian F1Fo ATP-synthase Date: September 14, 2020 Source: Institute of Science and Technology Austria ...

In mammalian cells, co-translational N-glycosylation is one of the most common covalent protein modifications. This essential reaction is catalysed by the oligosaccharyl-transferase complex (OST ...

In the development of the mammalian kidney, USC Stem Cell scientists from Andy McMahon's lab undertook a pair of complementary studies, published in the journal Development, that provide new ...

The first three-dimensional (3-D) structure of a human protein complex within intact mammalian cells has been obtained directly by A*STAR scientists. It could provide new opportunities in ...

A world-first cell atlas has opened a window into the complexity of the mammalian brain. The map details more than 5,000 cell-type clusters in the mouse brain and marks out their location.

A major international study, being presented today at the 62nd ERA Congress, reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to ...