Emerging findings in T cells indicate that nuclear receptors use a combination of activation and repression pathways to regulate the differentiation and function of distinct helper T cell subsets.

CD19-directed chimeric antigen receptor (CAR) T cells are clinically effective in a limited set of leukemia patients. However, CAR T-cell therapy thus far has been largely restricted to targeting ...

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve cell therapies.

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...