The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Methods: We used an established protocol to differentiate human THP-1 monocytes into M1 or M2 macrophages involving three distinct ... anti-human CD209 BV421, anti-human CD14 FITC and anti-human B2M ...

Conclusions These results describe a novel pathway where altered mitochondrial biology in JDM CD14+ monocytes lead to oxmtDNA production and stimulates ISG expression. Targeting this pathway has ...

1 Asthma and Allergy Research Institute Inc and Centre for Asthma ... Queensland Institute of Medical Research, Brisbane, Australia Background: CD14 functions as a multifunctional receptor for ...

Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand Department of Pharmacognosy and Pharmaceutical Botany, Faculty of ...

The following is a news release from THP. The Tennessee Highway Patrol will be conducting a Sobriety Roadside Checkpoint on US 412 in Madison County on February 9, 2025. Impaired driving is a ...

In the kidneys, such a system might also be present. In fact, we were able to co-localize TLR4 with CD14 at the apical brush border of rat proximal tubules, a site at which expression of both ...

Learn more› By Caitlin Giddings and Wirecutter Staff When it comes to gifts, many 1-year-olds aren’t picky. In fact, they may be as excited by the packaging as by what’s inside. (Save those ...

Human monocytic leukemia THP-1 cells were purchased from Conservation Genetics CAS Kunming Cell Bank and were originally from the American Type Culture Collection (ATCC) (31). CD14 + monocytes and ...

These cell populations play distinct roles in cardiovascular biology and disease and are affected by S100A8/A9 in different ways (Figure 1). Figure 1. Schematic representation of the potential effects ...