The activation and polarization of T cells play a crucial role in atherosclerosis and dictate athero-inflammation. The epigenetic enzyme EZH2 (enhancer of zeste homolog 2) mediates the H3K27me3 ...

The thymus plays a pivotal role in generating a highly-diverse repertoire of T lymphocytes while preventing autoimmunity. Thymus seeding progenitors (TSPs) are a heterogeneous group of multipotent ...

We also conducted immunofluorescence staining and functional experiments to examine the mechanism. This is an open access article distributed in accordance with the Creative Commons Attribution Non ...

Furthermore, because tetramer staining requires live T cells with functional TCRs, we were unable to perform immunofluorescence or immunohistochemical staining to identify mouse MAIT cells in fixed or ...

Objective The obesity epidemic and its metabolic complications continue to be a major global public health threat with limited effective treatments, especially drugs that can be taken orally. Peptides ...