However, owing to heterogeneity in tumours, single biopsies can create the ‘illusion of clonality’, whereby target neoantigens in a sampled subset of tumour cells seem to be clonal 1 when they ...

Research published in New Phytologist provides insights into why the invasive plant Japanese knotweed is so successful at ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Medical Dialogues team speaks with the lead authors of the research, Dr. Disha Chakraborty and Dr. Abhishek De from the ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

We describe two patients in whom malignant monoclonal T-cell lymphoproliferation developed after administration of chimeric antigen receptor (CAR) T-cell therapy with ciltacabtagene autoleucel ...

The basic principles for CLD include preliminary screening for high-yield cell pool, single-cell isolation and improvement of productivity, clonality and stability. With the development of modern ...

Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell ...

From bacteria to humans, adaptive immune systems provide learned memories of past infections. Despite their vast biological differences, adaptive immunity shares features from microbes to vertebrates ...