This localization enables enhanced cytolysis of tumor cells and promotes T-cell activation, proliferation, and survival within the tumor microenvironment. Diakines are available as a convenient ...

Reactivation of cytotoxic CD8 + T-cell responses has set a new direction for cancer immunotherapy. Neutralizing antibodies targeting immune checkpoint programmed cell death protein 1 (PD-1) or its ...

Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system. Regardless, in IgG4 related disease (IgG4-RD) ...

Fever persisted for 1 week despite treatment with amoxicillin. The purpuric rash and pulmonary symptoms regressed progressively after 10 days. Hepatic cytolysis regressed spontaneously as did the ...