Class II diterpene cyclases catalyze bicyclization of geranylgeranyl diphosphate. While this reaction typically is terminated via methyl deprotonation to yield copalyl diphosphate, in rare cases ...

A new labdane diterpene glucoside, curcumanggoside (1), together with nine known compounds, including labda-8 (17),12-diene-15,16-dial (2), calcaratarin A (3), zerumin B (4), scopoletin, ...

Cafestol and kahweol are coffee-specific diterpenes -- known for their potential to increase cholesterol levels. The diterpene concentrations in coffee from brewing machines considerably exceeded ...

One of the most common causes of allergic contact dermatitis are plants. This article highlights potential irritant plants and products and examines current treatments.

Researchers from the University of Georgia found a new drug that may boost the brain's ability to heal itself after injury. The discovery could lead to significant advances in treating traumatic ...

Diterpene Esters Phorbol, daphnane, and diterpene are chemical irritants collectively known as diterpene esters. They are among the most irritant of plant-derived chemicals. [32] ...

Medicinal Aconitum species produce diterpene alkaloids with diverse oxidation catalyzed by yet unknown enzymes.

In recent years, there has been increasing interest in studying gut microbiome-derived hydrolases in relation to oral drug metabolism, particularly focusing on natural product drugs. Despite the ...

B. S. Vogel, M. R. Wildung, G. Vogel, R. Croteau, Abietadiene synthase from grand fir (Abies grandis). cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase ...