BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

Pancreatic cancer is one of the most lethal cancers, with only about 12% of patients surviving five years after diagnosis. A ...

Cancer is associated with fibroblasts at all stages of disease progression. This Review discusses the pleiotropic actions of cancer-associated fibroblasts (CAFs) on tumour cells and postulates ...

Researchers have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic ...

Fibroblasts produce the glycosaminoglycans, collagens, elastic fibers, reticular fibres and glycoproteins that can be seen in the extracellular matrix. When tissue damage has occurred, ...

Fibroblasts reside in the lining and sublining of the synovium. In the rheumatoid synovium, fibroblast hyperplasia takes place at both locations.

Trisomy is a genetic condition characterized by the presence of an extra chromosome. This means that the affected person has ...

Before the researchers could transplant fibroblasts, they characterized differences in volar and non-volar fibroblasts under pressure. They isolated and grew fibroblasts collected from volunteers’ ...