Cancer is associated with fibroblasts at all stages of disease progression. This Review discusses the pleiotropic actions of cancer-associated fibroblasts (CAFs) on tumour cells and postulates ...

导读胆管癌（Cholangiocarcinoma，CCA）是起源于胆道的高致死性恶性肿瘤，5 年总体生存率仅 7%-20%，并且其发病率在全球范围内持续上升。多数患者确诊时已为晚期，无法接受根治性手术，且免疫检查点阻断（Immune ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

Pancreatic cancer is one of the most lethal cancers, with only about 12% of patients surviving five years after diagnosis. A ...

This new article publication from Acta Pharmaceutica Sinica B , discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts. Idiopathic pulmonary ...

The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

The Advanced Wound Care Summit is an ideal forum to showcase how FibroBiologics is pioneering the next generation of wound healing through our fibroblast-based technology," said Mr. O’Heeron. "Our ...

Fibroblasts reside in the lining and sublining of the synovium. In the rheumatoid synovium, fibroblast hyperplasia takes place at both locations.

Fibroblasts produce the glycosaminoglycans, collagens, elastic fibers, reticular fibres and glycoproteins that can be seen in the extracellular matrix. When tissue damage has occurred, ...

Before the researchers could transplant fibroblasts, they characterized differences in volar and non-volar fibroblasts under pressure. They isolated and grew fibroblasts collected from volunteers’ ...