Mixed lineage leukemia (MLL)-fusion proteins can induce acute myeloid leukemias (AMLs) from either hematopoietic stem cells (HSCs) or granulocyte–macrophage progenitors (GMPs), but it remains ...

Patients 1 and 2 had bone marrow cytogenetic analyses and reverse transcriptase-polymerase chain reaction (RT-PCR) screening for chromosomal translocations performed at initial presentation ...

Each year, about 100,000 patients worldwide are affected by T-cell leukemias and lymphomas. Adults with relapsed T-cell cancers have limited therapeutic options and five-year survival rates of 7 ...

More information: Safia Safa-Tahar-Henni et al, Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines, Leukemia (2024).

They found that mutant MLL proteins bind at different sites in myeloid and lymphoid lineage leukemias, underscoring how the lineage context can influence the genetic targets of mutant MLL proteins in ...

He noted that childhood cancer survival rates can reach 80 per cent with early diagnosis, timely access to treatment, and a ...

Every day a child in Romania is diagnosed with cancer. Every day a family in our country enters the battle with a disease that can be beaten if it is detected early and a personalized treatment ...

The National Coordinator, National Cancer Control Programme, Federal Ministry of Health and Social Welfare, Dr. Uchechukwu Nwokwu, says 7.2% out ...