This lysosomal "TRAP" (lysoTRAP) shows efficient viruses and variants infection inhibition potential in cell, mouse, hamster, and human lung organoid models. Phys.org Story by Chen Na ...
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Even more fascinating is the intricate relationship between lysosomal exocytosis ...
The protein Spns1 helps transport fat molecules out of lysosomes, preventing harmful buildup and offering insights for rare ...
LCA-0321 is a LYTAC degrader designed to specifically bind and rapidly deplete anti-TSHR autoantibodies, the underlying cause of Graves’ disease and its extrathyroidal manifestations, including ...
The enzyme replacement therapy (ERT) market is projected to grow significantly, rising from US$ 10,707.6 million in ...
Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...
Augustine Therapeutics appoints Gerhard Koenigas Chief Executive Officer as Company Prepares to Enter the ClinicIndustry veteran Gerhard Koenig, ...
Structure of the lysosomal chloride-proton transporter CLC-7 in complex with OSTM1 Structure of the 9-1-1 checkpoint clamp being loaded onto DNA by the 9-1-1 checkpoint clamp Son Y., Kenny T.C., Khan ...
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