The different effects of short- and long-term inhibition of another downstream regulator of SMC proliferation, c- myc, on neointimal formation in rats were recently reported by Edelman et al. 43 In ...

In the past decade, efforts to improve blood pressure control have looked beyond conventional approaches of lifestyle modification and drug therapy to embrace interventional therapies. Based upon ...

The link between cytoskeletal actin dynamics and correlated gene activities was unclear. However, the discovery that globular actin polymerization liberates myocardin family transcriptional ...

The newly formed neointimal lesions consist of both SMC and foam cell-like macrophages. Here we assessed the hypothesis that the use of potent anti-restenotic drugs, like sirolimus and paclitaxel, may ...