The different effects of short- and long-term inhibition of another downstream regulator of SMC proliferation, c- myc, on neointimal formation in rats were recently reported by Edelman et al. 43 In ...

Neointimal hyperplasia is a major cause of early restenosis after intervention in the cardiovascular system. For example, restenosis secondary to neointimal hyperplasia occurs in up to 50% of patients ...

Unfortunately, all of these procedures injure the vascular endothelium, which impairs its ability to produce nitric oxide (NO) and ultimately leads to neointimal hyperplasia and restenosis.

At 6 months, less neointimal hyperplasia was found at both the proximal and distal anastomoses. This included the prosthetic wall, suture region, and arterial wall.

Neointimal hyperplasia is a known complication following aorta interventions. In this study, our hypothesis was that inhibiting phosphoglycerate kinase 1 (PGK1) could effectively reduce aortic ...