This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...

AlphaGenome, an artificial intelligence system just released by Google DeepMind in London, aims to show how even tiny changes ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

The mysterious majority – as much as 98 percent – of our DNA do not code for proteins. Much of this “dark matter genome” is thought to be nonfunctional evolutionary leftovers that are just along for ...

To identify noncoding mutations that are associated with functional effects in cancer, Dr. Ideker’s team turned back to TCGA data and carried out a systematic analysis of 930 tumors, integrating ...

Noncoding RNAs as master regulators in brain. According to Debra Silver, a developmental neurobiologist at the Duke University School of Medicine in North Carolina, researchers have for nearly half a ...

Noncoding mutations contribute to autism risk Date: December 13, 2018 Source: Simons Foundation Summary: A whole-genome sequencing study of nearly 2,000 families has implicated mutations in ...

The most commonly recognized function of RNA is to code for proteins in the body, but 75% of the human genome generates noncoding RNA that does not code for proteins. A substantial portion of these ...

Long noncoding RNAs (lncRNAs) could be a byproduct of transcription (i), a scaffold linking proteins (ii) or a guide bringing proteins to specified parts of the genome (iii).

Association studies provide genome-wide information about the genetic basis of complex disease, but medical research has focused primarily on protein-coding variants, owing to the difficulty of ...

MISNOMER: A peptide (pink, with its predicted binding to a muscle protein) is translated from an RNA thought to have been noncoding. D.M. ANDERSON ET AL., CELL, 160:595-606, 2015. The paper D.M.

New research shows modifying noncoding RNA with N6-methyladenosine allows the RNA exosome to recognize a specific noncoding RNA associated with the genomic site that encodes the heavy chain of ...